Detection of prednisolone in vitreous following systemic administration
نویسندگان
چکیده
منابع مشابه
Nephrogenic systemic fibrosis following gadolinium administration.
To the Editor: Nephrogenic systemic fibrosis (NSF) is an emerging medical entity in patients with renal disease, which results in progressive cutaneous and systemic fibrosis. It is a rare disorder that has been recognized in patients with renal impairment since 2000.1 Patients with NSF demonstrate symmetric dermal and subcutaneous fibrosis evidenced by increasing skin induration on clinical exa...
متن کاملSystemic Treatment of Vitreous Inflammation
Non infectious vitreous inflammation is often vision threatening and can be associated with potentially life-threatening systemic conditions. Treatment is often challenging as it involves systemic medications that can be associated with adverse effects. The classes of drugs are ever expanding and include corticosteroids, antimetabolites, alkylating agents, T-cell and calcineurin agents, biologi...
متن کاملThe intravitreal penetration of ceftriaxone in man following systemic administration.
Seventeen patients who underwent vitreal surgery received ceftriaxone (Rocephin) 1-2 g intramuscularly at various time intervals before surgery. Specimens of serum and vitreous were assayed for ceftriaxone concentrations both by bioassay and high pressure liquid chromatography. All patients had detectable vitreous (and serum) ceftriaxone concentrations at all time periods. Vitreous ceftriaxone ...
متن کاملPharmacokinetics of linezolid in human non-inflamed vitreous after systemic administration.
OBJECTIVES To determine the concentration-time curves of linezolid in serum and vitreous from 24 patients undergoing vitrectomy. METHODS Vitrectomy was performed 1, 2, 4, 8 and 12 h after infusion of 600 mg of linezolid in 20 patients divided into groups of four. Four additional patients were studied 12 h after two separate oral doses of 600 mg of linezolid. Serum samples were obtained 1 h af...
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ژورنال
عنوان ژورنال: Eye
سال: 1998
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.1998.259